Pesquisa | BVS IEC

1.

Messenger RNA vaccines against SARS-CoV-2.

Topol, Eric J.

Cell ; 184(6): 1401, 2021 03 18.

Artigo em Inglês | MEDLINE | ID: mdl-33740443

2.

Polygenic Risk Scores Expand to Obesity.

Torkamani, Ali; Topol, Eric.

Cell ; 177(3): 518-520, 2019 04 18.

Artigo em Inglês | MEDLINE | ID: mdl-31002792

3.

Unveiling the Role of the Most Impactful Cardiovascular Risk Locus through Haplotype Editing.

Lo Sardo, Valentina; Chubukov, Pavel; Ferguson, William; Kumar, Aditya; Teng, Evan L; Duran, Michael; Zhang, Lei; Cost, Gregory; Engler, Adam J; Urnov, Fyodor; Topol, Eric J; Torkamani, Ali; Baldwin, Kristin K.

Cell ; 175(7): 1796-1810.e20, 2018 12 13.

Artigo em Inglês | MEDLINE | ID: mdl-30528432

4.

High-Definition Medicine.

Torkamani, Ali; Andersen, Kristian G; Steinhubl, Steven R; Topol, Eric J.

Cell ; 170(5): 828-843, 2017 Aug 24.

Artigo em Inglês | MEDLINE | ID: mdl-28841416

5.

Whole-Genome Sequencing of a Healthy Aging Cohort.

Erikson, Galina A; Bodian, Dale L; Rueda, Manuel; Molparia, Bhuvan; Scott, Erick R; Scott-Van Zeeland, Ashley A; Topol, Sarah E; Wineinger, Nathan E; Niederhuber, John E; Topol, Eric J; Torkamani, Ali.

Cell ; 165(4): 1002-11, 2016 May 05.

Artigo em Inglês | MEDLINE | ID: mdl-27114037

6.

From mRNA sensing to vaccines.

Fauci, Anthony S; Merad, Miriam; Swaminathan, Soumya; Hur, Sun; Topol, Eric; Fitzgerald, Kate; Reis e Sousa, Caetano; Corbett, Kizzmekia S; Bauer, Stefan.

Immunity ; 54(12): 2676-2680, 2021 12 14.

Artigo em Inglês | MEDLINE | ID: mdl-34739870

7.

Individualized medicine from prewomb to tomb.

Topol, Eric J.

Cell ; 157(1): 241-53, 2014 Mar 27.

Artigo em Inglês | MEDLINE | ID: mdl-24679539

8.

Foundation models for generalist medical artificial intelligence.

Moor, Michael; Banerjee, Oishi; Abad, Zahra Shakeri Hossein; Krumholz, Harlan M; Leskovec, Jure; Topol, Eric J; Rajpurkar, Pranav.

Nature ; 616(7956): 259-265, 2023 04.

Artigo em Inglês | MEDLINE | ID: mdl-37045921

9.

A foundation model for generalizable disease detection from retinal images.

Zhou, Yukun; Chia, Mark A; Wagner, Siegfried K; Ayhan, Murat S; Williamson, Dominic J; Struyven, Robbert R; Liu, Timing; Xu, Moucheng; Lozano, Mateo G; Woodward-Court, Peter; Kihara, Yuka; Altmann, Andre; Lee, Aaron Y; Topol, Eric J; Denniston, Alastair K; Alexander, Daniel C; Keane, Pearse A.

Nature ; 622(7981): 156-163, 2023 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-37704728

10.

The personal and clinical utility of polygenic risk scores.

Torkamani, Ali; Wineinger, Nathan E; Topol, Eric J.

Nat Rev Genet ; 19(9): 581-590, 2018 09.

Artigo em Inglês | MEDLINE | ID: mdl-29789686

11.

Why we can thank a polio emergency for the birth of intensive care.

Topol, Eric.

Nature ; 618(7964): 234-235, 2023 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-37280288

12.

Variant-proof vaccines - invest now for the next pandemic.

Burton, Dennis R; Topol, Eric J.

Nature ; 590(7846): 386-388, 2021 02.

Artigo em Inglês | MEDLINE | ID: mdl-33558746

13.

The Proportion of SARS-CoV-2 Infections That Are Asymptomatic : A Systematic Review.

Oran, Daniel P; Topol, Eric J.

Ann Intern Med ; 174(5): 655-662, 2021 05.

Artigo em Inglês | MEDLINE | ID: mdl-33481642

14.

Protective alleles and modifier variants in human health and disease.

Harper, Andrew R; Nayee, Shalini; Topol, Eric J.

Nat Rev Genet ; 16(12): 689-701, 2015 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-26503796

15.

Prevalence of Asymptomatic SARS-CoV-2 Infection : A Narrative Review.

Oran, Daniel P; Topol, Eric J.

Ann Intern Med ; 173(5): 362-367, 2020 09 01.

Artigo em Inglês | MEDLINE | ID: mdl-32491919

16.

Early detection of pancreatic cancer and AI risk partitioning.

Maitra, Anirban; Topol, Eric J.

Lancet ; 403(10435): 1438, 2024 Apr 13.

Artigo em Inglês | MEDLINE | ID: mdl-38615682

17.

The clinical potential of counterfactual AI models.

Lee, Su-In; Topol, Eric J.

Lancet ; 403(10428): 717, 2024 Feb 24.

Artigo em Inglês | MEDLINE | ID: mdl-38401957

18.

Deep learning detects impending organ injury in the clinic.

Topol, Eric J.

Nature ; 572(7767): 36-37, 2019 08.

Artigo em Inglês | MEDLINE | ID: mdl-31367025

19.

Rare coding variants in the phospholipase D3 gene confer risk for Alzheimer's disease.

Cruchaga, Carlos; Karch, Celeste M; Jin, Sheng Chih; Benitez, Bruno A; Cai, Yefei; Guerreiro, Rita; Harari, Oscar; Norton, Joanne; Budde, John; Bertelsen, Sarah; Jeng, Amanda T; Cooper, Breanna; Skorupa, Tara; Carrell, David; Levitch, Denise; Hsu, Simon; Choi, Jiyoon; Ryten, Mina; Sassi, Celeste; Bras, Jose; Gibbs, Raphael J; Hernandez, Dena G; Lupton, Michelle K; Powell, John; Forabosco, Paola; Ridge, Perry G; Corcoran, Christopher D; Tschanz, JoAnn T; Norton, Maria C; Munger, Ronald G; Schmutz, Cameron; Leary, Maegan; Demirci, F Yesim; Bamne, Mikhil N; Wang, Xingbin; Lopez, Oscar L; Ganguli, Mary; Medway, Christopher; Turton, James; Lord, Jenny; Braae, Anne; Barber, Imelda; Brown, Kristelle; Pastor, Pau; Lorenzo-Betancor, Oswaldo; Brkanac, Zoran; Scott, Erick; Topol, Eric; Morgan, Kevin; Rogaeva, Ekaterina.

Nature ; 505(7484): 550-554, 2014 Jan 23.

Artigo em Inglês | MEDLINE | ID: mdl-24336208

20.

Machines and empathy in medicine.

Topol, Eric J.

Lancet ; 402(10411): 1411, 2023 10 21.

Artigo em Inglês | MEDLINE | ID: mdl-37865458

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Messenger RNA vaccines against SARS-CoV-2.

Polygenic Risk Scores Expand to Obesity.

Unveiling the Role of the Most Impactful Cardiovascular Risk Locus through Haplotype Editing.

High-Definition Medicine.

Whole-Genome Sequencing of a Healthy Aging Cohort.

From mRNA sensing to vaccines.

Individualized medicine from prewomb to tomb.

Foundation models for generalist medical artificial intelligence.

A foundation model for generalizable disease detection from retinal images.

The personal and clinical utility of polygenic risk scores.

Why we can thank a polio emergency for the birth of intensive care.

Variant-proof vaccines - invest now for the next pandemic.

The Proportion of SARS-CoV-2 Infections That Are Asymptomatic : A Systematic Review.

Protective alleles and modifier variants in human health and disease.

Prevalence of Asymptomatic SARS-CoV-2 Infection : A Narrative Review.

Early detection of pancreatic cancer and AI risk partitioning.

The clinical potential of counterfactual AI models.

Deep learning detects impending organ injury in the clinic.

Rare coding variants in the phospholipase D3 gene confer risk for Alzheimer's disease.

Machines and empathy in medicine.